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how genetics work

Discussion in 'Breeder Discussion' started by ben brockton, Feb 3, 2013.

  1. TDK

    TDK CH Dog Staff Member

    Everything is indeed genetically given and potentially resultant. What varies is how it manifests, and that is what needs to be tended to over time. That's called selectivity. Bottom line.
     
  2. Rock n Rye

    Rock n Rye CH Dog

    One of the most important things to success, selectivity, check your inbox my friend.
     
  3. ELIAS'PISTOLA

    ELIAS'PISTOLA CH Dog

    Best quote yet, add it too the list TDK..
     
  4. Carson

    Carson Pup

    incorrect, sir.

    Selectivity


    Heritability

    Heritability measures the fraction of phenotype variability that can be attributed to genetic variation. This is not the same as saying that this fraction of an individual phenotype is caused by genetics. In addition, heritability can change without any genetic change occurring, such as when the environment starts contributing to more variation.
     
  5. mccoypitbulls

    mccoypitbulls Underdog

    these are the days of our lives...lol...sorry yall..
    this is a great thread with great intelect..thank you all for sharing your study and experience with us.
     
  6. TDK

    TDK CH Dog Staff Member

    Carson, I think you're adding text to what I said and meant. Point being (again), that selectivity is the bottom line when it comes to any and all variables as lineage continues (or doesn't). Selectivity is the steering wheel for genetic flow, phenotype and all given physiology through the generations.
     
    Last edited by a moderator: Dec 12, 2014
  7. CHAMP

    CHAMP Big Dog

    Correct, sir.

    Sent from my microwave using Tapatalk
     
  8. Carson

    Carson Pup

    No, what you said and I quote, "What varies is how it manifests, and that is what needs to be tended to over time. That's called selectivity," is not called selectivity. Perhaps you meant different but as stated, the variation in genetics and how it is tended is NOT selectivity.

    This statement, "Selectivity is the steering wheel for genetic flow, phenotype and all given physiology through the generations," i would not disagree with since it does not relate to variances that can or can not change, by contributions or lack there of, due to genetics.
     
  9. TDK

    TDK CH Dog Staff Member

    I think you might still be awry of the fact that I'm not correlating genetics or phenotypes with selectivity in the way you are deriving the meaning. My first post was to indicate what I said in my second post......that selectivity IS the steering wheel by which one tends to the quality of the genetic flow throughout and over time (generations). Selectivity is the means by which one applies those variances as either desirable or not and continues with the more desirable. In effect, the steering wheel for future quality with what is given genetically. I meant no other correlation.
     
  10. Carson

    Carson Pup

    It is good to think but I am not awry of anything. My intent was to point out the difference between selectivity and heritability, regardless of your interpretation/wording of the former.

    *happy face*
     
  11. TDK

    TDK CH Dog Staff Member

    Alright, and that, you did, indeed. NP
     
  12. Carson

    Carson Pup

    COLOR:
    As with all genetic traits, every animal inherits one copy of each locus(locations on the chromosomes) from each of its parents. Each of these loci is responsible for one or more traits either independently, or in conjunction with another locus. All of them act on the pathways that produce the two major pigments, phaeomelanin and eumelanin, or affect the distribution of those pigments.

    The combined effect of all these loci (Agouti, Brown, Extension, etc.) is the color of the dog. Due to the complex interactions of these genes, it is possible for dogs to carry hidden colors which may appear in their offspring. Over the past several years, scientists at VetGen and elsewhere have determined the actual genes associated with many of these loci, and identified the mutations responsible for the different versions (alleles) of these genes. The fruit of this work are the tests available for many of the common coat colors and traits.



    The diagram below illustrates the relationships among the major loci (A, B, E and K) involved in determining coat color. The sections that follow describe the role these loci and others play in the coat color tests that VetGen offers. These tests demonstrate that while a dog may exhibit certain color or colors, it may also be carrying other hidden colors in its genetic code that can show up in later generations.

    How do the A, B, E, and K loci affect each other in determining coat color?

    The accompanying graphic helps to illustrate the interactions of the genes at these four loci in a hierarchy in terms of their role in coat color. If a circle is filled with color, it means the color of the dog has been determined at that point. If a circle is still white, it means information about an additional gene is required.

    10mncdt.jpg

    The first locus to look at is the E locus. The gene at this locus is responsible for black masks when present as well as most shades of yellow and red. Any dog that is "ee" will be some shade of yellow to red, and everything happening at the A, B, and K loci will be hidden until the next generation. If the dog has any E or Em alleles, then it will not be yellow and we must look next at the K locus.

    There are three versions, or alleles, of the K locus: KB, kbr, and ky. If a dog has even a single copy of KB (KBKB, KBky, KBkbr) it will be solid colored in the pigmented areas, and we go directly to the B locus to determine color. Everything happening at the A locus in these dogs is hidden until the next generation. If a dog is kyky, it will not be brindled, and we go next to the A locus to see which alleles are expressed. If a dog is kbrkbr, or kbrky, it will nearly always be brindled and we look next at the A locus to see the background color and pattern of that brindling.



    The A locus has at least four alleles. There are direct tests available for Ay (fawn or sable),"a" (recessive black), and "at" (tan points). There is no direct test for the Wild type (think wolf pattern) allele which is designated aw.Any dog which has at least one copy of Ay (and no KB) will be fawn or sable, either with or without brindling.Any dog that is "aa" (and no KB) will be black. Any dog that is atat or ata (and no KB) will have tan points, either with or without brindling.



    The next stop is the B locus. Any dog which is "bb" will be have brown fur in those areas that would otherwise be black. This holds true for both solid colored and agouti-patterned animals.


    The D locus (not shown in the diagram) can alter the intensity of pigment. Animals which are "dd" exhibit grey or blue fur in place of black, and light tan or "Isabella" in place of brown. This tan is similar to some AY shades but lacking any banding or black tips on individual hairs.
     
  13. Carson

    Carson Pup

    Gladly. Now some who are reading may say, "who cares," well heritability actually matters when talking about genetics and I will let Mr. Gary Hammonds explain the game trait in layman's terms..

    Gameness is some what relative to many factors or combination of these: time, place, environment, condition of the animal and type of stress are all factors that will check a dog*s oil. Many dogs have shown to be short of Gameness at one time and come back to show Dead Game at a later date, while others have shown exceptional Gameness one day and later quit cold.
     
  14. poorfarmkennels

    poorfarmkennels Big Dog

    Damn Carson I was hoping to not study this morning. Lol
     
  15. Sounds like you're living the life. My mother was a primary school teacher. I am impressed that a number of your family members were involved in such a noble profession. There use to be "Hog Catching" competitions around these parts but they put an end to that about 15 or 20 years ago. I had a female , given to me by an oldtimer , whose sire won a trophy or two from outings like these. She was a smart dog. Any pictures of the 10 month old? I really like dogs that push weight. Matching weight, in my opinion , is analogous to minimum wage; and you know what the critique about minimum wage is right: "We would like to pay you less but legally we can't"! Yes, i like my American Classics too. I am in the market for a 62 impala. Mileage? Never crossed my mind when i would take the 63 or 65 impalas for a spin. Are you yanking my chain again oldgoat?
     

  16. Looks like an interesting book. I did go through the source material provided (complete bibliography?) but had some trouble verifying passages and in what context they were used; and yes, i did see the little caveat at the bottom of the web page. As a result, i stumbled on to this:

    A Bit of Tarnish on Marijuana's Benign Reputation » American Scientist


    http://www.reuters.com/article/2014/11/18/us-usa-washington-marijuana-idUSKCN0J22JF20141118

    How do you respond to these narratives? Btw, I've got a great story about a litter , some oldtimers and weed.
     
  17. ELIAS'PISTOLA

    ELIAS'PISTOLA CH Dog

    The breeder wears no clothes...Please share, Chickenonachain...
     
  18. old goat

    old goat CH Dog

    no chicken i'm not pulling your chain . they were English teachers to . next time you fill up check the mileage on the truck just to see what they got back in the 60's . now on the a bit of tarnish . well you know what i think lol . they did a study to see how addicting cannabis is and found that it was no more addicting as chocolate . you can get a psychological addiction to it but it's like chocolate just stop eating and your fine . the science and health effects are known very well . people have been smoking for along time with no problems . there is a lot of gold mental studies and test done all the time in medical states . i thought you would know propaganda when you read it . they try to scare people but it just doesn't work when they lie . now for the edible problem . parents need to be responsible and put things away . to many households have alcohol sitting out and you don't hear them crying . you can't die from cannabis you will just feel strange and tired for 5-8 hours . all you have to do is eat sweets and drink orange juice to even out the effects or eat 3 black peeper corns . why won't they have baying and catching contest where you live ? around here they have traps on the sides of the roads trying to get them . there is just to many and they really tear up a lot of stuff .
     
  19. old goat

    old goat CH Dog

  20. bounty

    bounty Big Dog

    TDK on your analogy of Selectivity being the steering wheel for genetic flow, i would like to throw in that the genes are the road and roads do limit where you can go. And although where you steer is important, if you are on the wrong road you will never get to where you want to go.
     

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